- Vomiting
- Loss of appetite,
- Weight loss
- Soft and/or gray stools
- Weakness and listlessness
Often times these symptoms are similar to other conditions and
the liver remains untreated until it becomes evident that the animal
is experiencing advanced liver disease. As the disease worsens toxins begin to build up in the body and the signs of liver failure become more evident:
- Jaundice
- Convulsions
- Confusion
- Swollen abdomen from fluid accumulation
While advanced liver disease can be treated effectively, it is always best to identify the signs and begin treatment early, saving your pet from unpleasant symptoms and you from costly medical bills.

The good news is that liver
is remarkable in its ability to regenerate itself and so many animals
go on to live normal, healthy lives after experiencing liver failure.
However, do your pet a favor - if the above symptoms persist for several days, take your companion to your veterinarian. If pharmaceutical drugs such as steroids are necessary, ask your vet if your pet would benefit from natural treatments such as milk thistle or antioxidants to combat the harsh effects of NSAID and steroids. See the Natural Treatments section for more information on supporting the liver with nutraceuticals.
Diagnosis
A blood test will reveal abnormalities in the liver and may indicate
the extent of the damage. A liver biopsy may be necessary to determine
the cause and severity of the problem.
Preventing Liver Disease
The best way to prevent liver diseases is to avoid exposing your
pet to toxins and chemicals. Some common potential liver toxins
are:
- Nonsteroidal antiinflammatory drugs such as aspirin, Rimadyl,
Teogesic or Feldene
- Cortisone (steroid) compounds
- Heavy metals, i.e. mercury from some deep-sea fish and lead
from paint chips
- Phenobarbital (Note: For seizures, a safe alternative to phenobarbital
is potassium bromide.)
Natural Treatments
Diet plays an important role in the healing of the
liver. Small, frequent meals which are low in fat and contain easily
digestible grains will help minimize the work that the liver must
do while it heals.
An important function of the liver is to remove toxins from the body. When liver disease strikes, toxins build up inside the animal’s blood stream and can cause extreme illness and even death. Subcutaneous fluids can help flush the body of excess toxins, while antibiotics can address bacterial infections that often develop as a result of liver failure.
There are several nutraceuticals that aid in treating liver diseases
and are especially beneficial to restoring the health of the liver
when steroids and other prescription drugs are used.
Milk thistle is often the herb of choice among holistic
veterinaraians because it is a powerful antioxidant.
Milk thistle as a healing agent
Silybum
marianum (milk thistle) is one of the most important herbal liver
tonics and restoratives for your pet. Scientific analysis shows
that milk thistle contains silymarin - a powerful antioxidant which
can block the entry of toxins into the liver and remove them at
cellular level, resulting in regeneration of liver cells and improved
liver function.
More potent as an antioxidant than Vitamin E, silymarin
acts as a scavenger on free radicals (molecules that cause cell
damage), as well as increasing levels of glutathione (a prime antioxidant
that protects major organs) and inhibiting the formation of damaging
leukotrienes (an inflammatory agent). Silymarin also stimulates
the production of new liver cells to repair damage caused by disease.
In addition to milk thistle (silymarin), there are several other nutrients which are beneficial to the liver:
- Burdock - Used for centuries as a blood purifier and cleanser.
- Natrium Phosphate - A tissue salt that helps to assimilate fats and promote the flow of bile from the gall bladder.
- Natrium Sulphate - A tissue salt often recommended to detoxify the liver.
- Dimethyglycine (DMG) – An amino acid that helps rebuild liver cells and encourages the elimination of toxins in the body.
- Pyridoxal 5'Phospate – The active form of B6, an essential vitamin that is not easily broken down in pets with compromised livers.
- Vitamin B12 – An important vitamin needed for proper digestion and absorption of food.
- Choline Citrate – A chemical used by the liver to move fats in and out of the cells, which is crucial to liver health.
- Methionine – An amino acid needed for proper detoxification of the liver.
- N-Acetyl-L-Cysteine – An amino acid that is aids in the removal of toxins from the liver.
- Turmeric Extract – A potent antioxidant and anti-inflammatory.
- Alpha Lipoic Acid – A powerful antioxidant that enhances the antioxidient effects of Vitamins C and E.
- Coenzyme Q10 – Also known as Vitamin Q, this nutrient is essential for healthy liver function.
- Antioxidants - Chemicals that capture damaging free radicals in the body and encourage healthy liver cells.

To aid in the healing of the liver, we suggest the following product containing milk thistle and other beneficial nutrients:
LiverAid by PetAlive

LiverAid is an herbal and homeopathic remedy that contains nutrients which improve liver functions and help to eliminate toxins from the body.
To purchase or read more about LiverAid...
Immunity and Liver Support by PetAlive
Immunity and Liver Support strengthens and improves immune system and liver functioning in dogs and cats. Helps to counter the harmful effects of frequent vaccinations and antibiotic treatment.
To purchase or learn more about Immunity and Liver Support...
Detox Plus from PetAlive
This natural herbal remedy helps to prevent the buildup of harmful toxins (i.e. insecticides, cigarette smoke, flea collars, food preservatives to name a few) in your pet's body. Detox Plus improves liver functioning, metabolism, thyroid health and your pet's ability to eliminate toxins.
To purchase or read more about Detox Plus...
Hepagen-C for Dogs

Hepagen-C
provides the beneficial herbs milk thistle and tumeric with antioxidants
and important nutrients for Phase I and Phase II liver detoxification.
Hepagen-C can be used long term, if necessary.
To purchase or read
more about Hepagen-C...

Hepagen-F
provides the beneficial herbs milk thistle and tumeric with antioxidants
and important nutrients for Phase I and Phase II liver detoxification.
Hepagen-F can be used long term, if necessary.
To purchase or read
more about Hepagen-F...
To learn more about specific liver diseases in cats, click on these links: Hepatic Lipidosis, General Hepatitis and Cholagiohepatitis.
For additional support, ask your vet if an antioxidant formula would help the overall health of your pet.
Small Animal Antioxidant
This
formula combines vitamins A, C, E, beta carotene, and selenium (all
potent free-radical scavengers) with grape seed extract, lipoic
acid and silymarin (all potent antioxidants). It can be used alone
or in combination with Hepagen.
To purchase or read
more about Small Animal Antioxidant...
If your pet has a liver condition you'd like to learn more about, send us an email and will try to include it in future updates to this website. See our Contact Us page.
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