NSAIDs and Blood Thinners

I am giving my 47 lb Lab your Cell Advance 880 antioxidant formula.  He also takes 25mg Deramaxx every other day for arthritis. With regards to the caution statement on the bottle, “do not take with blood thinners” – is this a problem for him?

Thanks for your help.

Deramaxx is a non-steroidal anti-inflammatory drug and it should not be given with steroids or aspirin–like drugs.  

Cell Advance 880 does contain Rutin, which inhibits platelet aggregation, therefore acting as a blood thinner. So they probably should not be used together. If your dog is on Deramaxx for arthritis and you would prefer a more naturopathic approach, try glucosamine and fish oil supplements. Glycoflex III or ArthriSoothe-Gold both contains glucosamine, chondroitin and Green Lipped Mussel, all of which are very anti-inflammatory and improve flexibility and elasticity of cartilage. Super EPA with fish oil is both anti-inflammatory and immune supportive.

Acupuncture may be another avenue to try it also reduces pain and works especially well in dogs with arthritis. Best of luck.

Regards,

Colleen Smith DVM,CVA

Follow-up Question

Dear Dr. Smith,

Thanks for your reply. He is already on Glyco-Flex III and he is currently taking the Cell Advance  880 in hopes of helping with his cognitive functions. My vet suggested we find a supplement with Lipoic Acid, which Cell Advance 880 has. The warning on the bottle with regard to blood thinners refers to Quercetin found in the product.

Am I correct to give him this with regards to his cognitive problems -? (he exhibits some but not all symptoms of cognitive dysfunction – he’s 14 ½ years old.

Are you suggesting then to find a substitute for the Deramaxx in order to keep him on Cell Advance 880?

I had shown the product to my vet first, before I started my lab on it, and he said it would be fine to give it to him.

I would appreciate your help with this  – thank you.

Hello Diane,

I can’t find direct research on how Quercetin and Rutin affect the Deramaxx in the body. You may continue with the information that the supplement does have a blood thinning affect and make a decision based on that information. Small Animal Anti-oxidant from Thorne also contains alpha lipoic acid but does not contain the Quercetin or Rutin.  Canine Geriatric Basic Nutrients by Thorne is also a good alternative for overall health and cognitive issues.

As a holistic veterinarian I often recommend alternatives to Deramaxx because of it’s affect on the liver and gastro-intestinal health. I’ve seen great results with acupuncture and chiropractic treatments and have been able to improve quality of life without NSAIDs.

Regards,

Dr. Smith

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